VENTILATORY RESPONSE TO CARBON DIOXIDE IN PATIENTS WITH HOMOZYGOUS SICKLE-CELL DISEASE
نویسندگان
چکیده
منابع مشابه
Ventilatory response to carbon dioxide in patients with homozygous sickle-cell disease.
The ventilatory response to carbon dioxide was measured by a rebreathing technique in 21 Nigerians who had homozygous sickle-cell disease. The slope of the carbon dioxide response curve was obtained by plotting the ventilation at successive half-minute intervals against the corresponding mean end-tidal PCO2. Our results showed that sickle-cell patients are as sensitive to carbon dioxide as are ...
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As long as ventilatory studies were the only approach to the problem of dyspncea in cardiac patients, its explanation seemed to be found in pulmonary changes secondary to congestive failure (Peabody and Wentworth, 1917). Combined ventilatory and circulatory measurements in such patients showed the problem to be more complex. Reduced ventilatory capacity appears to become a significant factor in...
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Background: Sickle cell disease is a genetic disorder of hemoglobin causing myriad of pathology including anemia. The purpose of this study was to evaluate the baseline values of steady state hemoglobin and packed cell volume as a guide to managing the early recognition of hemolytic crises in sickle cell anemia. Methods: A cross-sectional study was conducted among the sickle cell patients atte...
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A comparative study was made of ventilatory and airway occlusion pressure (P0.1; a parameter reflecting respiratory center output) responses to carbon dioxide between 11 patients with bronchial asthma and 10 chronic obstructive lung disease (COLD). Increments in ventilatory volume (VE) produced by a rise in end-tidal CO2 pressure (PETCO2), i.e. delta VE/BSA/delta PETCO2, were smaller in 4 patie...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1976
ISSN: 0007-0912
DOI: 10.1093/bja/48.3.249